A Levitzki Selected Research

RTKI cpd

5/2006	Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase.
9/2001	Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor.
5/2001	Signal therapy for RAS-induced cancers in combination of AG 879 and PP1, specific inhibitors for ErbB2 and Src family kinases, that block PAK activation.

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A Levitzki Research Topics

Disease

9	Neoplasms (Cancer) 01/2016 - 07/2000
2	Glioblastoma (Glioblastoma Multiforme) 05/2006 - 09/2001
2	Breast Neoplasms (Breast Cancer) 05/2001 - 01/2000
2	Sarcoma (Soft Tissue Sarcoma) 05/2001 - 07/2000
1	Carcinogenesis 01/2016
1	Colorectal Neoplasms (Colorectal Cancer) 01/2016
1	Vascular System Injuries 09/2001
1	Head and Neck Neoplasms (Head and Neck Cancer) 05/2001
1	Psoriasis (Pustulosis Palmaris et Plantaris) 07/2000

Drug/Important Bio-Agent (IBA)

5	Phosphotransferases (Kinase)IBA 10/2001 - 07/2000
3	ErbB Receptors (EGF Receptor)IBA 05/2006 - 05/2001
3	RTKI cpdIBA 05/2006 - 05/2001
3	TyrphostinsIBA 09/2001 - 01/2000
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2016 - 05/2001
2	Cisplatin (Platino)FDA LinkGeneric 11/2006 - 09/2001
2	DNA (Deoxyribonucleic Acid)IBA 11/2006 - 05/2001
2	Pharmaceutical PreparationsIBA 05/2006 - 07/2000
2	Tyrosine (L-Tyrosine)FDA Link 05/2001 - 07/2000
2	src-Family KinasesIBA 05/2001 - 07/2000
1	Interleukin-11 (Interleukin 11)IBA 01/2016
1	CytokinesIBA 01/2016
1	Interleukin-6 (Interleukin 6)IBA 01/2016
1	Insulin ReceptorIBA 01/2016
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 01/2016
1	Interleukin-23 (Interleukin 23)IBA 01/2016
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016
1	Insulin (Novolin)FDA Link 01/2016
1	ChemokinesIBA 01/2016
1	IGF Type 1 Receptor (IGF 1 Receptor)IBA 01/2016
1	Checkpoint Kinase 1IBA 11/2010
1	Antineoplastic Agents (Antineoplastics)IBA 11/2006
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 11/2006
1	Oncogene Proteins (Oncogene Protein)IBA 10/2001
1	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 09/2001
1	Tyrosine Kinase InhibitorsIBA 09/2001
1	deoxyuridine triphosphateIBA 09/2001
1	poly(lactide) (polylactic acid)IBA 09/2001
1	Biological ProductsIBA 09/2001
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 05/2001
1	Epidermal Growth Factor (EGF)IBA 05/2001
1	Proteins (Proteins, Gene)FDA Link 05/2001
1	CSK Tyrosine-Protein KinaseIBA 05/2001
1	LigandsIBA 05/2001
1	tyrphostin AG825IBA 05/2001
1	AG-879IBA 05/2001
1	Insulin-Like Growth Factor I (IGF-1)IBA 12/2000
1	AgarIBA 07/2000

Therapy/Procedure

2	Therapeutics 05/2001 - 01/2000
1	Drug Therapy (Chemotherapy) 11/2010